When we discuss bacterial infections, we often think of exotoxins—those soluble proteins actively secreted by bacteria—while overlooking endotoxins, which are more insidious but equally dangerous.
Endotoxin refers to a component of the outer cell membrane of Gram-negative bacteria called lipopolysaccharide (LPS). LPS is the biologically active portion of naturally occurring endotoxin complexes.
Researchers at North Carolina State University have shown a link between the size of cockroach home infestations and the levels of both allergens and endotoxins in those homes, with lowering roach ...
Physicians Committee for Responsible Medicine: FDA Endotoxin Testing Update Falls Short for Nonanimal Methods
A recent guidance update from the U.S. Food and Drug Administration (FDA) on pyrogen and endotoxins testing represents a missed opportunity to meaningfully advance alternatives to horseshoe-crab-blood ...
For over a century, one invisible chemical has misled scientists, contaminated breakthrough experiments, and disrupted drug development. In this video, we uncover the hidden story of endotoxins—from ...
Palladium-Item: BETMAT Launches High-Performance Sustainable Endotoxin Testing Services To Meet Evolving Industry Needs
BETMAT Launches High-Performance Sustainable Endotoxin Testing Services To Meet Evolving Industry Needs
News Medical: Microfluidic automation of endotoxin testing: How it works with the Sievers Eclipse
What are the benefits of microfluidic automation? Microfluidic automation is the most straightforward available form of automation for endotoxin testing on the market today. It streamlines endotoxin ...
Microfluidic automation of endotoxin testing: How it works with the Sievers Eclipse
In this episode of C&EN Uncovered, host Craig Bettenhausen speaks with C&EN assistant editor Laurel Oldach about the use of horseshoe crab blood in pharmaceutical endotoxin testing, the challenges of ...