Different gene families such as caspases, inhibitor of apoptosis proteins, B cell lymphoma (Bcl)-2 family of genes, tumor necrosis factor (TNF) receptor gene superfamily, or p53 gene are involved and/or collaborate in the process of apoptosis.
ascopubs.org: Targeted Induction of Apoptosis in Cancer Management: The Emerging Role of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Receptor Activating Agents
Targeted Induction of Apoptosis in Cancer Management: The Emerging Role of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Receptor Activating Agents
Mitochondria are involved in apoptosis, necrosis, pyroptosis, and iron death. At present, the research on cell apoptosis is relatively thorough, and the mechanism of mitochondria in it has also been ...
Unlike apoptosis, necrosis strongly signals the immune system to target and cleanup the remains of the dying cells, Shapiro said. "This suggests that treatments that promote necrosis may improve ...
Apoptosis is a peer-reviewed journal devoted to basic and clinically-oriented investigations into programmed cell death. Stimulates research on the basis of mechanisms of apoptosis and its role in various human disease processes. Investigates links to cancer, autoimmune disease, viral infection, AIDS, cardiovascular disease, neurodegenerative disorders, osteoporosis and ageing. Encourages ...
Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions. It is also one of the most studied topics among cell biologists. An understanding of the underlying mechanism of apoptosis is important as it plays a pivotal role in the pathogenesis of many diseases. In some, the problem is due to too much apoptosis, such as in the case of ...
Apoptosis is a peer-reviewed journal devoted to basic and clinically-oriented investigations into programmed cell death. Stimulates research on the basis of ...